{"created":"2023-05-15T11:16:05.074343+00:00","id":2225,"links":{},"metadata":{"_buckets":{"deposit":"5edb4a01-f8ad-4c58-8c3b-4a5b96d0a159"},"_deposit":{"created_by":3,"id":"2225","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2225"},"status":"published"},"_oai":{"id":"oai:tsc.repo.nii.ac.jp:00002225","sets":["7:59:93"]},"author_link":["12025","12024","12026","12020","12023","12019","12021","12027","12022"],"item_2_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-12-20","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"12","bibliographicPageStart":"7","bibliographicVolumeNumber":"34","bibliographic_titles":[{"bibliographic_title":"聖徳栄養短期大学紀要"}]}]},"item_2_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡辺, 悟"}],"nameIdentifiers":[{"nameIdentifier":"12019","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"三沢, 尚子"}],"nameIdentifiers":[{"nameIdentifier":"12020","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坂上, 宏"}],"nameIdentifiers":[{"nameIdentifier":"12021","nameIdentifierScheme":"WEKO"}]}]},"item_2_creator_7":{"attribute_name":"著者名よみ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ワタナベ, サトル"}],"nameIdentifiers":[{"nameIdentifier":"12022","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ミサワ, ナオコ"}],"nameIdentifiers":[{"nameIdentifier":"12023","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"サカガミ, ヒロシ"}],"nameIdentifiers":[{"nameIdentifier":"12024","nameIdentifierScheme":"WEKO"}]}]},"item_2_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"WATANABE, SATORU","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12025","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MISAWA, NAOKO","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12026","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SAKAGAMI, HIROSHI","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12027","nameIdentifierScheme":"WEKO"}]}]},"item_2_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_2_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Green coffee contains a large amount of polyphenols, especially caffeoyl quinic acid (CQA) related compounds. Using TOYOPEARL HW-40F column chromatography, five fractions (I～V) were separated from green coffee bean extract. HPLC technique demonstrated that Frs. II and III were mainly composed of CQA, whereas Frs. IV and V were mainly cmposed of diCQA. We measured the DPPH radical scavenging activity of these fractions. Frs. III and V had higher DPPH radical scavenging activities than green coffee bean extract. We also investigated the effect of these fractions on the cytotoxicity and the nitric oxide (NO) production by LPS-activated mouse macrophage-like Raw 264.7 cells. Noncytotoxic concentration of Fr. III (CQA fraction) inhibited NO production by activated Raw 264.7 cells. Fr. IV (diCQA fraction) showed higher cytotoxicity and increased NO production at lower concentration. The present study demonstrated that green coffee bean extract contains numerous substance which regulate the function of activated macrophages.","subitem_description_type":"Other"}]},"item_2_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00128690","subitem_source_identifier_type":"NCID"}]},"item_2_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"SEITOKU JUNIOR COLLEGE OF NUTRITION"},{"subitem_text_language":"en","subitem_text_value":"SEITOKU JUNIOR COLLEGE OF NUTRITION /"}]},"item_2_text_2":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_text_value":"原著"}]},"item_2_text_3":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Original"}]},"item_2_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"聖徳栄養短期大学"},{"subitem_text_value":"聖徳栄養短期大学"},{"subitem_text_value":"明海大学歯学部"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-09-26"}],"displaytype":"detail","filename":"KJ00004086609.pdf","filesize":[{"value":"404.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"url":"https://tsc.repo.nii.ac.jp/record/2225/files/KJ00004086609.pdf"},"version_id":"d908d03c-811e-4a51-af17-7718f6aef5e7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Chlorogenic acid","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DPPH radical","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Macrophage-like cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"クロロゲン酸類のDPPHラジカル消去活性とマウスマクロファージ様細胞に対する影響について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"クロロゲン酸類のDPPHラジカル消去活性とマウスマクロファージ様細胞に対する影響について"},{"subitem_title":"DPPH Radical Scavenging Activity of Chlorogenic Acid Related Compounds and their Effects against Mouse Macrophage-like Cells","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["93"],"pubdate":{"attribute_name":"公開日","attribute_value":"2003-12-20"},"publish_date":"2003-12-20","publish_status":"0","recid":"2225","relation_version_is_last":true,"title":["クロロゲン酸類のDPPHラジカル消去活性とマウスマクロファージ様細胞に対する影響について"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-15T13:27:22.900944+00:00"}